Postdoctoral Fellow in Neurobiology (University of Luxemburg)

Contract Type: Fixed Term Contract Duration: 24 Month About the LCSB The University of Luxembourg is an international research university with a distinctly multilingual and interdisciplinary character. The Luxembourg Centre for Systems Biomedicine (LCSB) is an interdisciplinary research centre of the University of Luxembourg. We conduct fundamental and translational research in the field of Systems Biology and Biomedicine – in the lab, in the clinic and in silico. We focus on neurodegenerative processes and are especially interested in Alzheimer’s and Parkinson’s disease and their contributing factors. The LCSB recruits talented scientists from various disciplines: computer scientists, mathematicians, biologists, chemists, engineers, physicists and clinicians from more than 50 countries currently work at the LCSB. We excel because we are truly interdisciplinary, and together we contribute to science and society. The University of Luxembourg has the following vacancy at the Luxembourg Centre for Systems Biomedicine (LCSB) - Molecular & Functional Neurobiology group: Postdoctoral Fellow Successful candidates will join the Molecular & Functional Neurobiology group, led by Prof. Anne Grünewald, which studies the genetic and non-genetic causes of neurodegeneration and neuroinflammation in Parkinson’s disease. Specifically, the group explores the contribution of intra- and intercellular mitochondrial signaling to these processes. For more information, please visit our website. The Postdoctoral fellow will contribute to the implementation of the “mitoERsgnl” project, which explores the role of ER-mitochondria signaling in Parkin-associated Parkinson´s disease. Your role Generation/maintenance of induced pluripotent stem cells and subsequent differentiation into dopaminergic neurons Study of calcium metabolism Assessment of cellular and mitochondrial function using advanced imaging techniques and molecular biology methods (including RNA-seq) Data analysis, data interpretation and reporting of results Participate in knowledge dissemination activities through the preparation of scientific publications or presentations in scientific venues Participate in funding applications (support hypothesis generation, conception, and grant writing) Participate in teaching activities (seminars and practicals) Support and tutoring of activity of students For further information, please contact Prof. A. Grünewald at anne.gruenewald@uni.lu. Use the job title and reference number mentioned above in the subject line of your email. Your profile PhD in Life Sciences, Neurosciences, Molecular Biology or related field with solid lab experience (+5 years) Strong interest in interdisciplinary research and cellular models of neurodegeneration Proven track record studying human induced pluripotent stem cell models, with practical experience in neuronal (and glial) differentiation protocols Good command of molecular biology methods Experience in RNA-seq analysis is considered an advantage Knowledge in intermediary metabolism and application of 13C-Isotope assisted metabolomics Experience with high-content image analysis and subsequent data handling (coding skills in MATLAB and/or R are considered as assets) Skills to autonomously conduct data analysis with solid understanding of statistics Excellent written and oral communication skills in English with proven experience in the writing of grants and scientific publications Excellent team-working, interpersonal skills, and ability to collaborate with local and international partners Enthusiasm and commitment to research Ability to think ahead as well as to troubleshoot We offer Multilingual and international character. Modern institution with a personal atmosphere. Staff coming from 90 countries. Member of the “University of the Greater Region” (UniGR) A modern and dynamic university. High-quality equipment. Close ties to the business world and to the Luxembourg labour market. A unique urban site with excellent infrastructure A partner for society and industry. Cooperation with European institutions, innovative companies, the Financial Centre and with numerous non-academic partners such as ministries, local governments, associations, NGOs … How to apply Applications should include: Detailed Curriculum Vitae including a list of publications Cover letter mentioning the reference number Copies of diploma and transcripts Name and addresses of three referees Early application is highly encouraged, as the applications will be processed upon reception. To ensure full consideration, please apply by 28th of February 2025 ONLINE formally through the HR system. Applications by Email will not be considered. All qualified individuals are encouraged to apply. In line with our values, the University of Luxembourg promotes an inclusive culture. We encourage applications from individuals of all backgrounds and are dedicated to upholding equality and respect for our employees and students. General information: Contract Type: Fixed Term Contract 24 Month Work Hours: Full Time 40.0 Hours per Week Location: Campus Belval Internal Title: Postdoctoral researcher Job Reference: UOL07086 The yearly gross salary for every Postdoctoral Researcher at the UL is EUR 83099 (full time). If you apply for this position please say you saw it on Academicoxy

Contract Type:

Fixed Term Contract

Duration:

24 Month

About the LCSB

The University of Luxembourg is an international research university with a distinctly multilingual and interdisciplinary character.

The Luxembourg Centre for Systems Biomedicine (LCSB) is an interdisciplinary research centre of the University of Luxembourg.
We conduct fundamental and translational research in the field of Systems Biology and Biomedicine – in the lab, in the clinic and in silico. We focus on neurodegenerative processes and are especially interested in Alzheimer’s and Parkinson’s disease and their contributing factors. The LCSB recruits talented scientists from various disciplines: computer scientists, mathematicians, biologists, chemists, engineers, physicists and clinicians from more than 50 countries currently work at the LCSB. We excel because we are truly interdisciplinary, and together we contribute to science and society.

The University of Luxembourg has the following vacancy at the Luxembourg Centre for Systems Biomedicine (LCSB) - Molecular & Functional Neurobiology group: Postdoctoral Fellow

Successful candidates will join the Molecular & Functional Neurobiology group, led by Prof. Anne Grünewald, which studies the genetic and non-genetic causes of neurodegeneration and neuroinflammation in Parkinson’s disease. Specifically, the group explores the contribution of intra- and intercellular mitochondrial signaling to these processes. For more information, please visit our website.

The Postdoctoral fellow will contribute to the implementation of the “mitoERsgnl” project, which explores the role of ER-mitochondria signaling in Parkin-associated Parkinson´s disease.

Your role

Generation/maintenance of induced pluripotent stem cells and subsequent differentiation into dopaminergic neurons
Study of calcium metabolism
Assessment of cellular and mitochondrial function using advanced imaging techniques and molecular biology methods (including RNA-seq)
Data analysis, data interpretation and reporting of results
Participate in knowledge dissemination activities through the preparation of scientific publications or presentations in scientific venues
Participate in funding applications (support hypothesis generation, conception, and grant writing)
Participate in teaching activities (seminars and practicals)
Support and tutoring of activity of students

For further information, please contact Prof. A. Grünewald at anne.gruenewald@uni.lu. Use the job title and reference number mentioned above in the subject line of your email.

Your profile

PhD in Life Sciences, Neurosciences, Molecular Biology or related field with solid lab experience (+5 years)
Strong interest in interdisciplinary research and cellular models of neurodegeneration
Proven track record studying human induced pluripotent stem cell models, with practical experience in neuronal (and glial) differentiation protocols
Good command of molecular biology methods
Experience in RNA-seq analysis is considered an advantage
Knowledge in intermediary metabolism and application of 13C-Isotope assisted metabolomics
Experience with high-content image analysis and subsequent data handling (coding skills in MATLAB and/or R are considered as assets)
Skills to autonomously conduct data analysis with solid understanding of statistics
Excellent written and oral communication skills in English with proven experience in the writing of grants and scientific publications
Excellent team-working, interpersonal skills, and ability to collaborate with local and international partners
Enthusiasm and commitment to research
Ability to think ahead as well as to troubleshoot

We offer

Multilingual and international character. Modern institution with a personal atmosphere. Staff coming from 90 countries. Member of the “University of the Greater Region” (UniGR)
A modern and dynamic university. High-quality equipment. Close ties to the business world and to the Luxembourg labour market. A unique urban site with excellent infrastructure
A partner for society and industry. Cooperation with European institutions, innovative companies, the Financial Centre and with numerous non-academic partners such as ministries, local governments, associations, NGOs …

How to apply

Applications should include:

Detailed Curriculum Vitae including a list of publications
Cover letter mentioning the reference number
Copies of diploma and transcripts
Name and addresses of three referees

Early application is highly encouraged, as the applications will be processed upon reception. To ensure full consideration, please apply by 28th of February 2025 ONLINE formally through the HR system. Applications by Email will not be considered.

All qualified individuals are encouraged to apply. In line with our values, the University of Luxembourg promotes an inclusive culture. We encourage applications from individuals of all backgrounds and are dedicated to upholding equality and respect for our employees and students.

General information: