PhD Position in Neuroscience
VU University of Amsterdam
Netherlands

Institution: Vrije Universiteit Amsterdam (VU Amsterdam)
Department: Molecular and Cellular Neuroscience, CNCR
Location: Amsterdam, Netherlands (Zuidas campus)
Contract Type: PhD (initially 1 year, extendable up to 4 years)
Salary: €3,059 – €3,881 gross per month (full-time, depending on year)
Application Deadline: Not specified (contact PI for details)
Contact: Harold MacGillavry – harold.macgillavry@vu.nl


Project Overview

  • Study the molecular mechanisms of synapse degeneration induced by ß-amyloid (Aß) in Alzheimer’s disease (AD).

  • Understand early synaptic pathology that precedes cognitive decline.

  • Techniques include:

    • Neuronal cell culture

    • Proteomics

    • CRISPR/Cas9 genome editing

    • Super-resolution microscopy

    • Whole-cell patch-clamp electrophysiology

  • Work in a diverse, interdisciplinary lab with access to core methodologies, models, equipment, and viral vectors from the start.

  • Training provided on-site and through specialized courses.


Key Responsibilities

  • Investigate molecular processes leading to pathological synapse dysfunction.

  • Analyze microscopy and electrophysiology data.

  • Publish in peer-reviewed journals and report progress to funding sources.

  • Contribute to teaching and supervision (~10% time).

  • Present research at international conferences.


Candidate Profile

  • Master’s degree in Life Sciences, Biomedical Sciences, Biophysics with a specialization in neuroscience.

  • Hands-on experience in molecular biology and cellular neuroscience.

  • Experience with super-resolution microscopy and/or electrophysiology is a plus.

  • Fluent in English, with strong written and oral communication skills.

  • Motivated, collaborative, and able to contribute to diverse and inclusive research environment.


Offer / Benefits

  • Full-time PhD for up to 4 years.

  • Salary: €3,059 – €3,881 gross per month (depending on year).

  • 8% holiday allowance and 8.3% end-of-year bonus.

  • Personalized benefits package, contribution to commuting expenses.

  • Training and career development opportunities in a leading neuroscience research environment.


About the Institution

  • CNCR participates in the Graduate School ONWAR at VU Amsterdam.

  • Faculty of Science: 11,000+ students, 1,600+ staff, 10 academic departments.

  • VU Amsterdam promotes diversity, inclusion, and socially engaged research.

  • Located in the Zuidas business district, with excellent transport links.


This PhD position is ideal for candidates interested in neuroscience, Alzheimer’s disease, synaptic biology, and cutting-edge molecular and cellular techniques.


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