DescriptionThe Yale PET Center/Department of Radiology and Biomedical Imaging at the Yale School of Medicine invites applications for tenure-track faculty position in chemistry. The primary role for this position is to establish a portfolio of novel radiopharmaceuticals for applications in radionuclide-based imaging research, therapies, and theranostics, with an emphasis on oncological applications. The selected candidate is expected to build an independent research program consistent with the mission and goals of the PET Center, attracting extramural funding, and collaborating with other investigators in Radiology, other Departments at Yale, and industrial partners in the development of radiopharmaceuticals for preclinical and clinical applications. The incumbent is also expected to work in close collaboration with a multidisciplinary team of scientists and clinicians to advance the applications of radionuclide-based imaging, therapy and theranostics in oncology, psychiatry/neurology, cardiology, immune and metabolic diseases, and other areas of disease research. The Yale PET Center, located on Howard Avenue in New Haven, CT, is a 22,000 sq. ft. facility established to advance the interests of Yale scientists, clinicians, and students in molecular imaging research. The Yale PET Center is comprised of a technologically advanced radiochemistry laboratory engaged in the development and use of a rich set of PET radiopharmaceuticals; and an imaging and data analysis section that oversees scanning procedures and optimizes data acquisition and analysis. The Yale PET Center collaborates with other School of Medicine departments to provide educational opportunities for doctoral and postdoctoral trainees. Collaborations with industry partners serve to advance the use of molecular imaging in new medication discovery and the development of new PET radiopharmaceuticals. Current research interests focus on disorders of the central nervous system (CNS), oncology, cardiology, and diabetes. QualificationsSuccessful candidates should have a Ph.D. in chemistry/radiochemistry, biology, materials science, or related fields. They should have experience and a track record of publications in one or more of the following areas: · Radiolabeling of compounds with positron-emitting isotopes applicable to PET and/or SPECT imaging. · Radiolabeling of compounds with alpha- or beta-emitting isotopes applicable to radionuclide therapy. · Experience with cell/tissue culture, autoradiography, microscopy, in vitro binding assays, and related techniques for early biological evaluation of candidate molecules. · Testing of biomedical hypotheses using nuclear imaging and/or radionuclide therapy in animal models and human subjects. · Processing of blood samples and radiometabolite analysis for pharmacokinetic analysis. Besides a strong background in the listed areas, candidates should have demonstrated capacity in the following areas: · Experience with cGMP manufacturing techniques for radiopharmaceuticals and use of automated radiosynthesis platforms. · Experience with analytical and quality control methods to verify the composition and characteristics of radiopharmaceutical products. · Strong verbal and written communication skills demonstrated by publication track record and experience with grant writing. · Mentoring skills for undergraduate and graduate students, interns and visiting scientists/students. Besides the requirements listed above, additional desired qualifications include: · Experience with multimodal imaging for synergistic use of functional and anatomical data. · Experience with imaging and therapy applications in neuroscience/neurology/psychiatry, cardiology, oncology, and immune function. Rank is dependent on the successful candidate’s qualifications. Application InstructionsApplication Instructions: Interested applicants should upload their CV and cover letter to the following website: apply.interfolio.com/161462. All final candidates will need to provide three letters of reference. Review of applications will begin immediately and continue until the position is filled.
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